Best 49ers Prop Bets for Week 11 Monday Night Football

Week 11 wraps up tonight in Mexico City with an NFC West showdown between the San Francisco 49ers and Arizona Cardinals. With a win, the 49ers can tie the Seahawks for first place in the division while the Cardinals look to make a late-season push out of third place. We’ll be looking at two player props for the 49ers that are worth taking a look at to end your week 11 on a high note.

Prop #1: George Kittle Over 3.5 Receptions (-140)

The Arizona Cardinals have had one of the worst defenses in the league this season in large part because of how bad their pass defense has been. Arizona is allowing an average of 25.8 points per game and 247.1 passing yards a game but most importantly the Cardinals have been getting exposed by tight ends all season.

Every starting tight end that has played against the Cardinals this season has put a huge stat line and I don’t think tonight will be any different since Kittle is a top tight end in the league and one of Jimmy Garoppolo’s favorite targets. The Cardinals allowed Travis Kelce to go catch eighth passes for 121 yards, Darren Waller had six catches for 50, and in two games this season against the Cardinals Noah Fant had 11 catches for 141 yards.

Kittle enters tonight averaging 4.14 receptions a game and this is only the second time this season his receptions total is at 3.5, the only other time it was that low this season he went over it. The last time the 49ers played an opponent who had a hard time stopping tight ends in the Atlanta Falcons, Kittle saw 10 targets that game and made eight receptions.

In the last two weeks, Kittle wasn’t targeted that often but I think tonight will be different and Garoppolo will look for him early and often throughout the game. Kittle has the ability to expose the Cardinals' defense repeatedly which makes me like him going over 3.5 receptions.

Prop #2: Brandon Aiyuk Over 54.5 Receiving Yards (-120)

Brandon Aiyuk enters this week with 80+ receiving yards in each of his last four games. He’s averaging 63 receiving yards a game and has gone over his yards prop in six of the nine games he’s played this season. Despite this offense having a ridiculous amount of weapons Aiyuk still sees a large majority of targets and plays designed for him each game.

In the last four games, Aiyuk has been targeted a combined 35 times and I don’t expect that to change tonight. With the complexity of the 49ers' offense, Aiyuk always seems to be able to break free multiple times a game, and tonight should truly be no different against a Cardinals team allowing 6.8 yards per reception.

I like the way Jimmy Garoppolo has been playing as of late and the fact that the Cardinals can’t focus on stopping one specific guy on offense due to the immense amount of talent the 49ers have makes me think that a guy like Aiyuk will be able to put up big numbers.